This is just a little reminder post for myself when creating web site that will use ASP.NET. For any web site on IIS to be able to utilize ASP.NET, FrontPage Server Extensions will have to be extended onto the web site. To do this go to [Adminsitrative Tools] > [Microsoft SharePoint Adminstrator].
Then click on "Extend" for the web site you want to enable ASP.NET on.
Fill in the required information then click "Submit".
ASP .NET 2.0